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| Registros recuperados: 98.244 | |
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| Couto Filho,Cristovão Colombo de Carvalho; Saliba,Eloísa de Oliveira Simões; Rodriguez,Norberto Mario; Barbosa,Geraldo Sérgio Senra Carneiro; Freitas,Regeane Martins de; Resende,Matheus Pinheiro Diniz. |
| The objective of this study was to evaluate the flow of nitrogenous compounds, protein degradability, rumen degradation of total carbohydrate and organic matter and microbial efficiency in heifers subjected to diets containing corn silage, sugarcane or Tifton. For this purpose, the 2,6-diaminopimelic acid (DAPA) technique was adopted and analytical procedures for amino acids by HPLC were adapted. Six rumen-fistulated Holstein-Zebu heifers with 480 kg of initial BW and at 24 months of age kept in individual tie stalls were assigned to two 3 × 3 Latin squares. Omasal digesta dry matter and microbial dry matter flows were determined using the isolated, purified and enriched lignin (LIPE®) and DAPA markers, respectively. Isolated bacteria from rumen showed on... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Corn silage; Flow of nitrogen compounds; HPLC; Microbial efficiency; Protein degradability; Sugarcane. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982015000500180 |
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| Graciani,F.S.; Ximenes,V.F.. |
| Apatone™, a combination of menadione (2-methyl-1,4-naphthoquinone, VK3) and ascorbic acid (vitamin C, VC) is a new strategy for cancer treatment. Part of its effect on tumor cells is related to the cellular pro-oxidative imbalance provoked by the generation of hydrogen peroxide (H2O2) through naphthoquinone redox cycling. In this study, we attempted to find new naphthoquinone derivatives that would increase the efficiency of H2O2 production, thereby potentially increasing its efficacy for cancer treatment. The presence of an electron-withdrawing group in the naphthoquinone moiety had a direct effect on the efficiency of H2O2 production. The compound 2-bromo-1,4-naphthoquinone (BrQ), in which the bromine atom substituted the methyl group in VK3, was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cancer Apatone™ Ascorbic acid Hydrogen peroxide 2-Bromo-1; 4-naphthoquinone. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000800003 |
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| Abbasi,Muhammad Athar; Aziz-ur-Rehman,; Qureshi,Muhammad Zahid; Khan,Farhan Mehmood; Khan,Khalid Mohmmed; Ashraf,Muhammad; Afzal,Iftikhar. |
| This manuscript reports the synthesis of a series of N-substituted derivatives of 2-phenitidine. First, the reaction of 2-phenitidine (1) with benzene sulfonyl chloride (2) yielded N-(2-ethoxyphenyl) benzenesulfonamide (3), which further on treatment with sodium hydride and alkyl halides (4a-g) furnished into new sulfonamides (5a-g). Second, the phenitidine reacted with benzoyl chloride (6) and acetyl chloride (8) to yield the reported N-benzoyl phenitidine (7) and N-acetyl phenitidine (9), respectively. These derivatives were characterized by infrared spectroscopy, ¹H-NMR, and EI-MS, and then screened against acetylcholinesterase, butylcholinesterase, and lipoxygenase enzyme, and were found to be potent inhibitors of butyrylcholinesterase alone. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 2-Phenitidine/inhibitor activity; Sulfonamides; Acetamide; Benzamide; Butyrylcholinesterase. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000100014 |
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| Gonzatto,Mateus Pereira; Böettcher,Gerson Nestor; Schneider,Leonardo André; Lopes,Ângelo Azeredo; Silveira Júnior,Jairo Camargo; Petry,Henrique Belmonte; Oliveira,Roberto Pedroso de; Schwarz,Sergio Francisco. |
| ABSTRACT: The 'Montenegrina' mandarin ( Citrus deliciosa Tenore) is widely cultivated in southern Brazil. This cultivar has a great tendency for alternate bearing, requiring thining of the fruit. However, the chemical thinners studied until now in this cultivar have not been successful. The objective of this research was to evaluate the effect of 3,5,6-trichloro-2-pyridinyloxyacetic acid (3,5,6-TPA) on the production and fruit quality of the 'Montenegrina' mandarin, in comparison with hand thinning and the options of chemical thinning previously studied. Hand thinning and no thinning were used as controls. Ethephon was applied in three doses: 200mg L-1, 300mg L-1 or 200mg L-1 + 3% urea; or 3,5,6-TPA, in four doses: 10, 20, 30 or 40mg L-1. Fruits of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Citrus deliciosa Ten. 3; 5; 6-TPA synthetic auxin ethephon alternate bearing. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001202078 |
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| Gomes,Urubatã E.; Oliveira,Diogo L. de; Berti,Luciana C.; Amaral,Olavo; Souza,Diogo O.; Wofchuk,Susana T.. |
| Scientific activity in Brazil has experienced an accelerated growth in the past decades, with an increase in productivity that greatly surpasses the international average. This growth has occurred mostly at the expense of centers of excellence in public universities, which account for the vast majority of the country's scientific output. The aim of this study was to evaluate the production of the Department of Biochemistry of a large public university in southern Brazil (Universidade Federal do Rio Grande do Sul), as well as to identify internal and external policies that have influenced this growing production profile. We have performed a historical analysis of the scientific output of this Department of Biochemistry, which accounts for a considerable... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Scientific productivity; Scientific growth profile; Biochemistry; UFRGS. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000300030 |
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| Ni, Zhijiang; Burks, Thomas F.. |
| Three dimensional (3D) reconstruction of the plant or tree canopy is an important step in order to measure canopy geometry, such as, height, width, volume, and leaf cover area. In this research, binocular stereo vision was used to recover the 3D information of the canopy. A revised camera calibration method was provided to calibrate the cameras in world coordinate system. Only two images were used to realize a dense reconstruction. These two images were firstly rectified to make sure the corresponding feature points in the left and right images were on the same horizontal line. An efficient large scale stereo matching (ELAS) algorithm was used to find the disparity map. The plant or tree canopy was finally reconstructed based on these calibrated camera... |
| Tipo: Info:eu-repo/semantics/article |
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| Ano: 2018 |
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/4358 |
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| Santos, Carlos Renato dos; Antonino, Antônio Celso Dantas; Heck, Richard John; Lucena, Leandro Ricardo Rodrigues de; Oliveira, Alex Cristóvão Holanda de; Silva, Antonio Samuel Alves da; Stosic, Borko; Menezes, Romulo Simões Cezar. |
| In this work, lacunarity analysis is performed on soil pores segmented by the pure voxel extraction method from soil tomography images. The conversion of forest to sugarcane plantation was found to result in higher sugarcane soil pore lacunarity than that of native forest soil, while the porosity was found to be lower. More precisely, this study shows that native forest has more porous soil with a more uniform spatial distribution of pores, while sugarcane soil has lower porosity and a more heterogeneous pore distribution. Moreover, validation through multivariate statistics demonstrates that lacunarity can be considered a relevant index of clustering and can explain the variability among soils under different land use systems. While porosity by itself... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lacunarity; Soil porosity; Impact of land use change. lacunarity soil porosity impact of land use change. |
| Ano: 2020 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAgron/article/view/42491 |
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| VASCONCELOS,PAULO M.; ONOE,ARTUR T.; KAWASHITA,KOJI; SOARES,ADALBERTO J.; TEIXEIRA,WILSON. |
| Laser heating 40Ar/39Ar geochronology provides high analytical precision and accuracy, mum-scale spatial resolution, and statistically significant data sets for the study of geological and planetary processes. A newly commissioned 40Ar/39Ar laboratory at CPGeo/USP, São Paulo, Brazil, equips the Brazilian scientific community with a new powerful tool applicable to the study of geological and cosmochemical processes. Detailed information about laboratory layout, environmental conditions, and instrumentation provides the necessary parameters for the evaluation of the CPGeo/USP 40Ar/39Ar suitability to a diverse range of applications. Details about analytical procedures, including mineral separation, irradiation at the IPEN/CNEN reactor at USP, and mass... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Geochronology; 40Ar/39Ar method; Irradiation; Calibration. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000200008 |
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| Luz Filho,Isaias Venancio da; Scheibel,Viviane; Appoloni,Carlos Roberto. |
| The aim of this study is to determine the amounts of radionuclides' activity present in samples of feed for young and adult chicken and feed for dairy and beef cattle, as well as in dicalcium phosphate (DCP) (CaHPO4), used as a nutritional supplement for animal feed. Radioactivity in these samples is due to the presence of the 238U and 232Th radioactive series, as well as their daughter. In addition, as it is for environmental samples, the activity of 40K should be an important source of radioactivity in all analyzed samples. Gamma rays were measured using a standard spectroscopy system, with a high-resolution HPGe detector. Measured activities in feed samples ranged from 0.23 to 1.51 Bq.kg-1, 0.67 to 4.21 Bq.kg-1, 0.29 to 1.63 Bq.kg-1 and 236 to 402... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gamma Ray Spectrometry; Natural radioactivity; Animal Feed; Dicalcium phosphate (DCP); Phosphate fertilizers. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100506 |
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| Massaro,Renato Ramos; Brohem,Carla Abdo; Almeida,Rebeca Leite de; Rivelli,Diogo Pineda; Miyake,Juliano Andreoli; Colquhoun,Alison; Barros,Silvia Berlanga de Moraes; Maria-Engler,Silvya Stuchi. |
| ABSTRACT Gliomas account for the majority of primary malignant brain tumors and present invasive behavior into adjacent healthy tissue. While 4-NC had previously shown to induce apoptotic cell death in a melanoma model, for the glioma model described in this paper 4-NC is cytotoxic for the cells with the induction of the autophagic pathway. Trypan blue exclusion assay showed that 4-NC was cytotoxic in a dose-dependent manner for A172 and T98G cell lines. IC10 and IC50 values were at 32 µM and 41 µM for A172 and T98G respectively. Inhibition of cell proliferation was observed by total cell counts and by cell cycle analysis by flow cytometry, with cell cycle arrest of A172 and T98G cell lines respectively in the G1/G0 and S phases of the cell cycle. 4-NC... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 4-Nerolidylcatechol; Glioblastoma; Cytotoxicity; Autophagy. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300618 |
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| Rodrigues,Carina Agostinho; Santos,Paloma Freire dos; Costa,Marcela Oliveira Legramanti da; Pavani,Thais Fernanda Amorim; Xander,Patrícia; Geraldo,Mariana Marques; Mengarda,Ana; Moraes,Josué de; Rando,Daniela Gonçales Galasse. |
| Abstract Background: There is still a need for new alternatives in pharmacological therapy for neglected diseases, as the drugs available show high toxicity and parenteral administration. That is the case for the treatment of leishmaniasis, particularly to the cutaneous clinical form of the disease. In this study, we present the synthesis and biological screening of eight 4-phenyl-1,3-thiazol-2-amines assayed against Leishmania amazonensis. Herein we propose that these compounds are good starting points for the search of new antileishmanial drugs by demonstrating some of the structural aspects which could interfere with the observed activity, as well as suggesting potential macromolecular targets. Methods: The compounds were easily synthesized by the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 2-aminothiazoles; Antikinetoplastids; Antileishmanial; Cutaneous; Target fishing. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100317 |
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| Souza,Eleane M.C. de; Silva,Ellon L. Da; Marinho,Andrey M.R.; Marinho,Patrícia S.B.. |
| The present work reports the isolation of eight compounds fromPestalotiopsis sp. EJC07 isolated as endophytic fromBauhinia guianensis, a tipical plant of the Amazon. The compounds (4S)-4,8-dihydroxy-1-tetralone (1), uracil (2), uridin (3), p-hydroxybenzoic acid (4), ergosterol (5), ergosterol peroxide (6), cerevisterol (7) and ducitol (8) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. The compound 1 is being reported for the first time in the genusPestalotiopsis. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: B. guianensis; Endophityc fungus; Pestalotiopsis; Tetralone. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100029 |
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| Sioli,Harald. |
| Constitui-se o presente trabalho da transcrição integral da palestra realizada pelo Dr. Harald Sioli (1910-2004) no Seminário da Amazônia, em 10 de agosto de 1990, quando numa última viagem ao Amazonas, ao completar 80 anos de idade, foi homenageado pelos colegas e a convite do INPA falou sobre "50 anos de pesquisas em limnologia na Amazônia" que, segundo suas próprias palavras, foram "os dias mais decisivos de minha vida". O texto pode ser dividido em duas partes: a primeira se refere à história pessoal - da chegada ao Brasil, de como descobriu a Amazônia e sobreviveu, no interior do Amazonas e Pará, à 2.ª Guerra Mundial, até se tornar pesquisador do INPA e firmar o Convênio INPA/Max Planck. A segunda parte fala da sua pesquisa em limnologia, fazendo... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amazônia; Limnologia; Clima equatorial; Quimismo. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672006000300001 |
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| Beltran-Leal,Adriana; Muñoz-Ruiz,Abraham; Esparza-Villalpando,Vicente; Castro,Yolanda; Pozos-Guillen,Amaury; Flores,Héctor. |
| The purpose of the study was to evaluate the antibacterial effect of protoporphyrin IX (PpIX) generated by the exogenous administration of 5-aminolevulinic acid or δ-ALA and activated with an argon laser over a planktonic and biofilm of Enterococcus faecalis (E. faecalis) as a pharmacological therapy alternative. A planktonic strain of E. faecalis was cultured with a solution of ∂-ALA (40 µg/mL)-thioglycolate solution for 13 min, and a biofilm of E. faecalis was cultured in a δ-ALA (80 µg/mL)-thioglycolate solution for 13 min. Then, both were irradiated with an argon laser. Finally, the antibacterial effect was evaluated by counting the CFU in planktonic form, and a LIVE/DEAD viability cell test. The production and accumulation of PpIX from exogenously... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biofilm; Photodynamic therapy; 5-aminolevulinic acid. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100572 |
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| Registros recuperados: 98.244 | |
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